Well first of all I interpret this as meaning "desk drawers". Drawers in dressing tables or the like are boring -- they contain sox and knickers. Well and detritus (like old spectacles) too, but not so much, at least in my case.
My "desk drawers" tough are numerous and full. To start with "desk" is a misnomer: I have a piece of kitchen worktop the length of one wall (8-9 feet of it!). On it is the usual desk stuff: pot of pens etc., phone, desk lamps, filing trays, jotter, Post-Its, monocular; plus my PC, screen, keyboard, printer etc. And literary society binders/work in progress. And currently a sleeping cat!
This is about half of my desktop (complete with cat) and showing one of the filing cabinets
The shelves over my "desk" have more desk and PC stuff (photo/label printers, speakers), a few teddy bears & friends, wifi router, postal scales and above that the most used reference books. Under the "desk" I have two "2-drawer" sized filing cabinets, each with one large drawer and three shallower ones. I also have a computer table (as a desk extension with another printer and scanner on it) and use the pull-out keyboard shelf as a desk drawer with A4 paper box lids as organisers. So ...
Contains standard office stationery like various sizes of envelope, compliments slips, business cards, postcards, rubber stamps, airmail stickers.
Left-hand Filing cabinet
Large bottom Drawer: various PC bits, spare wifi routers, spare analog phone, photo printer paper, multiple boxes of label sheets (a label size for everything!), PC cables.
Bottom shallow Drawer: More of the same: mostly boxes of adapters for PC and phones. And other PC odds and sods.
Middle Shallow Drawer: This is Anthony Powell Society drawer 2. Various AP Soc spares (till rolls for credit card terminal, coin bags, other banking spares). And the society's "In Tray".
Top Shallow Drawer: AP Soc drawer 1. Office stationery including compliments slips of various types, receipt book, supply of bookmarks, membership leaflets, postcards, etc.
Right-hand Filing Cabinet
Large Bottom Drawer: Household filing: bank statements, utility bills, tax, insurance, blah, blah, blah. Postcards and a few greetings cards. A supply of Trebor Extra Strong Mints. It's so full that I can't get any more in so there is a large overflow "awaiting filing" pile on th study floor along with more boxes of PC stuff, videos awaiting transcription etc.
Bottom Shallow Drawer: Pads of A4 paper, ring binder bags, coloured plastic files, odds & sods reusable envelopes.
Middle Shallow Drawer: Crammed with miscellaneous techie toot. Mobile phone chargers, camera battery chargers, earphones, dictaphone. Spare rechargeable batteries, camera spares, memory cards, memory sticks. Spare stocks of pencils, pencil leads, biros, marker pens. Several unused HP iPAQ and Palm handhelds. Spares for this and that. Boxes of business cards. Rolls of Dymo printer labels. Boxes of old keys. Spare wallet. Blah, blah, blah.
Top Shallow Drawer: Everyday desk stuff: pens, rulers, stapler, scissors, ball of elastic bands, ball of recycled string, lanyards, roller ruler, small screwdrivers and Allen keys, glue, sellotape. Spare batteries and fuses. Bank books etc. Odds and sods of foreign coinage and keys. Glasses cloth. Calculators.
And all that is without four printer paper boxes of stationery/office spares, and a lot more spare PC stuff in crates under my desk; and the old spare hifi stack; and boxes of printer paper, AP books for disposal/sale, paper recycling bin, shredder. No room for feet under the desk!!
Dare you tell us what's in your (desk) drawers?